膠原纖維(Collagen Fiber)是結(jié)締組織中分布最廣含量最多的一種纖維，廣泛分布于各種臟器，其中Ⅰ型膠原纖維主要是骨、皮膚、肌腱；Ⅱ型膠原纖維主要是軟骨膠原；Ⅲ型膠原纖維主要在胚胎組織、成人血管、胃腸道；Ⅳ型膠原纖維主要在基膜中。天狼星紅與其襯染液都是強(qiáng)酸性染料，易與膠原分子中的堿性基團(tuán)結(jié)合，吸附牢固。偏振光鏡檢查，膠原纖維有正的單軸雙折射光的屬性，與天狼星紅復(fù)合染色液結(jié)合后，可增強(qiáng)雙折射，提高分辨率，從而區(qū)分兩型膠原纖維。

       改良天狼星紅染色液（膠原纖維染色），為G1472-試劑B，主要用于各種組織病變時(shí)對(duì)膠原纖維異常變化的研究。在普通光學(xué)顯微鏡下心臟血管等組織的膠原纖維被染成紅色，在偏振光鏡下對(duì)各種纖維化病變的分型和分級(jí)研究有一定的幫助作用。

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標(biāo)題:Tryptophan 2,3-dioxygenase-positive matrix fibroblasts fuel breast cancer lung metastasis via kynurenine-mediated ferroptosis resistance of metastatic cells and T cell dysfunction

成員:Yongcan Liu, Shanchun Chen, Xueying Wan, Rui Wang, Haojun Luo, Chao Chang, Peijin Dai, Yubi Gan, Yuetong Guo, Yixuan Hou, Yan Sun, Yong Teng, Xiaojiang Cui, Manran Liu

論文因子:20.1 發(fā)表期刊:Cancer Communications pmid:39221971

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標(biāo)題:A mussel-inspired, antibacterial, antioxidant, injectable composite hydrogel for the sustain delivery of salvianolic acid B for the treatment of frozen shoulder

成員:Yan Yan, Xinhao Li, Chen Chen, Dedong Cui, Zhuo Wang, Ming Li, Yi Long, Jinming Zhang, Cheng Li, Zhiling Wang, Chuanhai Zhou, Zeyu Yao, Dan Wang, Jingyi Hou, Rui Yang

論文因子:18 發(fā)表期刊:Bioactive Materials pmid:39022185

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標(biāo)題:Integrating single-cell and spatial transcriptomics to elucidate the crosstalk between cancer-associated fibroblasts and cancer cells in hepatocellular carcinoma with spleen-deficiency syndrome

成員:Qiuxia Chen, Jin Luo, Jiahui Liu, He Yu, Meiling Zhou, Ling Yu, Yan Chen, Shijun Zhang, Zhuomao Mo

論文因子:4.5 發(fā)表期刊:Journal of Traditional and Complementary Medicine pmid:38707923

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標(biāo)題:Type I/II Immune Balance Contributes to the Protective Effect of AIF-1 on Hepatic Immunopathology Induced by Schistosoma japonicum in a Transgenic Mouse Model

成員:Lei Jiahui, Feng Yujie, Zheng Wenwen, Khamis Mwadini, Zhang Jinyuan, Hou Xiao, Guan Fei

論文因子:5.1 發(fā)表期刊:INFLAMMATION pmid:38554240

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標(biāo)題:Integrating single-cell and spatial transcriptomics to elucidate the crosstalk between cancer-associated fibroblasts and cancer cells in hepatocellular carcinoma with spleen-deficiency syndrome

成員:Qiuxia Chen, Jin Luo, Jiahui Liu, He Yu, Meiling Zhou, Ling Yu, Yan Chen, Shijun Zhang, Zhuomao Mo

論文因子:4.5 發(fā)表期刊:Journal of Traditional and Complementary Medicine

注意：以上文獻(xiàn) 僅供參考

改良天狼星紅染色液(膠原纖維染色)

改良天狼星紅染色液(膠原纖維染色)